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PLP is a cofactor for the synthesis of several neurotransmitters including serotonin, the catecholamines dopamine, norepinephrine, and epinephrine [critical enzyme is aromatic L-amino acid decarboxylase (AADC) which is encoded by the DDC gene and is more commonly referred to as DOPA decarboxylase], and -aminobutyric acid, GABA (critical enzyme is glutamic acid decarboxylase, GAD)

Comment: Dividing the elution in several fractions increases binding/washes efficiency

We next analyzed Tmprss2 / mice for IEC transcript levels of Gip and Glp1 , which showed no differences between male and female Tmprss2 / and WT mice at baseline (Supplemental Figure 4, A and B)