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In section V

In addition, administration of a JAK/STAT3 (Janus kinase-signal transducer and activator of transcription 3) signaling pathway inhibitor attenuated mechanical and thermal hyperalgesia, inhibited reactive astrocytes, and restored normal expression levels of astrocytic GLT-1 in the spinal dorsal horn of NDRG2-overexpression rats

This study highlights PDA-based NPs as a promising platform for GI disorder therapies, with particular emphasis on ROS scavenging as a pivotal mechanism in IBD management

Contrastingly, in the TMEV-induced viral encephalitis epilepsy model, IDO knockout exhibited an opposing effect, resulting in a higher incidence of epilepsy [58]