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Similar results were obtained in GRK3 KO mice, when morphine tolerance to analgesia was unchanged whereas tolerance to high efficacy agonists, such as fentanyl or U50,488, was reduced (Terman et al., 2004
Schellekens, H
61 Roflumilast has been shown to reduce allergen-induced inflammation and stabilize lipopolysaccharide-induced systemic inflammation via decreasing inflammatory mediators and the expression of cell surface markers, particularly in chronic bronchitis, non-smoker women
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