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The temporal relationship among mitochondrial damage, lysosomal impairment, and activation of compensatory pathways such as autophagy also remains poorly understood [8]
Methods Systematic review We conducted a systematic review of population-based studies to investigate changes in incidence and prevalence of CD and UC across global regions over time
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3.1 Size and surface area The size of AgNPs is a critical determinant of their antimicrobial activity, as it directly affects their surface-area-to-volume ratio and interaction with bacterial cells
