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Antioxidants role is to eliminate free radicals, terminate chain reactions, and inhibit further oxidative reactions, while they themselves are oxidized ( Antioxidants are abundant in daily life, with major sources including endogenously synthesized antioxidants, such as water-soluble and lipid-soluble antioxidants and antioxidative enzymes;natural antioxidants from food, such as various types of flavonoids, flavanols, anthocyanins, etc

Murata H, Ihara Y, Nakamura H, et al

(89) observed that Klotho protein levels were markedly elevated in aromatase-deficient mice, while estrogen pretreatment normalized these levels, suggesting that estrogen may lead to a reduction in Klotho protein

Some individuals receive treatments occasionally during periods of increased stress, travel, or physical exertion, while others establish a more regular wellness routine