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Chemical Properties of Melatonin and Its Metabolites Indole serves as a core structure in various natural compounds, including the melatonin precursor tryptophan, serotonin, tryptamine, indole-3-acetic acid, and melatonin itself [43]

[DOI] [PMC free article] [PubMed] [Google Scholar] 136.Sun Y., Sun X., Li X., Li W., Li C., Zhou Y., Wang L., Dong B

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Previous study has reported that inhibition of RSK with a dihydropteridinone, BI-D1870, which is a potent RSK inhibitor, decreases cell migration and proliferation of A549 human lung adenocarcinoma cells, through phospho GSK 3 [14]