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Statements Author contributions MEHK: Conceptualization, Writing original draft, Writing review and editing

For instance, in a six-month randomized controlled trial of 72 patients with Friedreichs ataxia (a neurodegenerative disorder characterized by mitochondrial iron accumulation), 20 mg/kg/day DFP was well tolerated but higher doses (40 and 60 mg/kg/day) were associated with increased adverse events and worsening of ataxia symptoms (Pandolfo et al., 2014)

References [1].Moos RH, Brennan PL, Schutte KK, Moos BS

Diabetes 19:72728 [DOI] [PubMed] [Google Scholar] 30.Fitzpatrick DB, Hooper RE, Seife B
