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Future research should focus on clarifying the functional distinctions among its isoforms, elucidating the crosstalk between epigenetic regulation and metabolic signaling, and developing specific PGC-1 agonists for the treatment of metabolic and degenerative diseases

Despite observed density for the C-terminal His tag, it was left unmodelled

doi: 10.1002/path.4357, PMID: [DOI] [PubMed] [Google Scholar] 114

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