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Ethical approval All procedures performed in this study involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards

Replicability was confirmed across individual mice and cell cultures, with data points included if they met technical validity standards (e.g., perfusion, tissue preparation, staining, recordings, imaging)

however, its long-term efficacy remains uncertain

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