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Optimized libraries for CRISPR-Cas9 genetic screens with multiple modalities

Programmed Necrosis and Disease: We Interrupt Your Regular Programming to Bring You Necroinflammation

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Curcumin exerts antioxidant effects through multiple pathways, directly scavenging reactive oxygen species and reactive nitrogen species, reducing oxidative damage to cellular components, with its chemical structure, including two phenolic rings connected by a beta-diketone moiety, enabling it to neutralize free radicals and inhibit lipid peroxidation (Alisi et al., 2018