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Retention of 5-methyl-THF fortificant during breadmaking varied depending on the bread size (so on baking time) and it was only 50% of that of folic acid in breads of the same size 127

Folic acid is more affected than 5-methyl-THF owing to the different affinities of FBP for various vitamers

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(137) administered milk calcium-fortified yogurt to OVX mice for 6 weeks, observed the modulation of the glycine pathway and the elevated Lactobacilli , and monitored the decrease in Clostridiaceae by metabolome and genome techniques, which were directly related to enhanced spinal BMD