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Glycine supports healthy blood sugar balance and glucose metabolism, serves as the principal amino acid in collagen for the structure of the skin, bones, joints, blood vessels and connective tissue, and is one of the three amino acids required to create glutathione

Li et al., 2019)

Two subgroups of cytosolic GSTs have been characterized based upon their interaction with glutathione: the Y-GST group, which uses a tyrosine residue to activate glutathione, and the S/C-GST, which instead uses serine or cysteine residues

When toxic exposure or chronic inflammation is too high, Phase 1 rapidly uses up the liver's glutathione reserves, causing Phase 2 to come to a screeching halt