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It is important to note that, like the independent-metabolism pathway, the dependent-metabolism pathway is not the only mechanism that contributes to the development of atherosclerosis, and it may act together with multiple pathways to contribute to the disease (122)
Fibrates down-regulate IL-1-stimulated C-reactive protein gene expression in hepatocytes by reducing nuclear p50-NFBC/EBP- complex formation

doi: 10.1097/01.pra.0000452568.92449.3f

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