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Keywords: molybdenum (Mo), molybdenum cofactor (MoCo), molybdenum cofactor deficiency (MoCD), xanthine oxidase (XO), aldehyde oxidase (AO), sulfite oxidase (SOX), mitochondrial amidoxime-reducing component (mARC), hepatocellular carcinoma (HCC), non-alcoholic fatty liver disease (NAFLD) 1

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2010) and thus, astrocytes are the first parenchymal cells of the brain that encounter substances and drugs that enter the brain from the blood

2.2 ROS in sterile inflammation The release of local damage-associated molecular patterns (DAMPs) in response to tissue damage elicits enhanced cytokine production via sterile inflammation