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In differentiated cells, high levels of DNA methylation occurred in the CpG-rich promoters of pluripotency-related genes (Shi et al., 2008)
In a recent study, involving 33 PD patients, SIBO eradication with rifaximin resulted in lower GI motor fluctuations, but without ameliorating L-DOPA bioavailability ( 3 Future challenges and perspectives Despite the promising results of gut-directed therapies in PD, certainly, several questions remain open
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J Postgrad Pharm (Hosp Ed)
