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Concerning the TLRs pathways, the stimulus with different BCG loads (MOI 5, 10, 20, and 40) or with the specific agonists for TLR2 (Pam3CSK4), TLR4 (ultrapure LPS), or TLR9 (CpG 1826) were not able to induce B16-F10 cells to secrete inflammatory cytokines such as TNF-a ( Figure 2C ), IL-6 ( Figure 2D ) or IL-12 ( Figure 2E )

doi: 10.1007/s11033-024-09415-7 108 PaulkasE.VanagasT.LagunaviiusS.PajdienE.PetrikonisK.RastenytD

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