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SNX27 recruits CFTR to the retromer complex through PDZ-based interaction The mammalian retromer complex functions as a coat complex that regulates intracellular trafficking in general by interacting with sorting nexins (SNXs), which serve as adaptor proteins that link retromer to specific cargo or membrane domains 24,26,27,28

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Proc Natl Acad Sci U S A 97: 1148211487, 2000 [DOI] [PMC free article] [PubMed] [Google Scholar] 73.Gorressen S, Stern M, van de Sandt AM, Cortese-Krott MM, Ohlig J, Rassaf T, Godecke A, Fischer JW, Heusch G, Merx MW, and Kelm M

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