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Clinical studies of ozone treatment for gliomas are shown in Table 2

The modified peptide was deprotected/cleaved and macrocyclized as described above, followed by RP-HPLC purification and in vacuo lyophilization

GSH is a water-soluble tripeptide containing a -acyl amide bond and a thiol group, synthesized from Glu, Cys, and glycine(Gly), retaining the reducing thiol group of Cys, which gives GSH certain reducing properties and plays an important role in antioxidant defense (Kennedy et al., 2020