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Description
Accordingly, the clinical presentations regarding liver involvement include a wide spectrum, ranging from asymptomatic subtle morphological changes, simple acute self-limited hepatitis-like illness to autoimmune-like hepatitis, or even recurrent jaundice (in the presence of haemolysis), cirrhosis with or without portal hypertension and even acute liver failure

Lancet 376 , 124136 (2010)

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Required for collagen synthesis
