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Furthermore, establishing a comprehensive safety and tolerability profile, particularly regarding long-term use and potential drug-drug interactions in the elderly AD population who often take multiple medications, is crucial

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36,37 Group II chaperonins include the archaeal thermosome and eukaryotic CCT (chaperonin-containing TCP1, or called TriC), which are oligomers with eight to nine subunits with molecular weight 5761 kDa in each ring