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Description
El tratamiento conduce a una mejora de los factores de riesgo y los trastornos asociados a la obesidad como hipercolesterolemia, hipertrigliceridemia, diabetes mellitus tipo 2, intolerancia a la glucosa hiperinsulinemia e hipertensin, as como a una reduccin de la grasa visceral

Self-rated health and adverse events in CKD Clin J Am Soc Nephrol 9 12: 2044-51

Interestingly, in db/db mice with type 2 diabetes mellitus, treatment with metformin results in a twofold reduction in TMAO concentration and the generation of bacteria associated to TMAO precursors production [137]

Thus, the effect could be evaluated already after a few days and terminated if there is a lack of effect or continued if the effect is positive
