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IGF-I and -II had actions through the type 1 IGF receptor (IGF1R) demonstrated by Igf1r ko animals with 45% of wild type birth weight and no further effect when crossed with Igf1 ko animals

PubMed PMID: 16310594
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If affordability or insurance coverage for weight loss is an issue, you may qualify for a GLP-1 with another condition such as obstructive sleep apnea or type 2 diabetes, says Moreno
