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Contrary to previous research suggesting that 7-DHC is toxic due to its potential to undergo autoxidation, this study found that 7-DHC has pro-survival functions in cancer cells by shielding lipids from oxidation, thus preventing ferroptotic cell death [72]

Interestingly, inhibition of microglial activation and matrix metalloproteinases (MMPs) with minocycline reduced reperfusion injury (Liu et al., 2012

Based on this, in the subsequent I/R- and TMT-induced myocardial injury model, the drug not only enhanced GSH levels and GPX and GST activities to lower oxidative damage but also reduced TMT-induced pyroptosis and I/R-mediated apoptosis [205207]

Cell-Free Protein Synthesis Technology in NMR High-Throughput Structure Determination