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The information provided here is based on animal research extrapolation and anecdotal reports from researchers and enthusiasts in the community

Interestingly, C5L2, belonging to C3a, C5a, and formyl Met-Leu-Ph (fMLP) receptors related to the chemokine receptor family, also binds to C3a with a moderate affinity (247, 248)

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Animal studies show that HIIT enhances phagocytic capacity in type 1 diabetic rats (103) and reduces lung neutrophil infiltration in acute lung injury models by lowering bronchoalveolar lavage fluid (BALF) MPO levels, thereby alleviating inflammatory damage (104)