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Pro-inflammatory cytokines in the pathogenesis of IBD
The brain is largely formed by PUFAs with high sensitivity to lipid peroxidation (Nunomura et al., 2006), motor neurons are highly sensitive to OS (Simpkins and Dykens, 2008) and the CNS has a poor antioxidant capacity with low activity of protective enzymes such as glutathione peroxidase (GPx), catalase (CAT) or superoxide dismutase (SOD) and poor capacity for cell regeneration (Fischer and Maier, 2015
Journal of Movement Disorders, 9(2), 7179
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