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Description
In yeast, 12-hydroxyeicosatetraenoic acid (which is probably a product of GPX4 depletion in mammals) is a substrate for Atg8 (MAP1LC3 [microtubule-associated protein 1 light chain 3] in mammalian cells) lipidation required to activate autophagy [156]
Jocsak, G
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62 However, when the animals are pretreated with ferrous iron, not only is the nitration pathway enhanced, but LPO suddenly becomes a relevant part of the pathomechanism
