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Furthermore, these loci seem to overlap with other psychiatric disorders, specially schizophrenia (SZ) [20]
In rat studies, Selank administration has been shown to alter the gene expression of GABA receptors, causing them to have a greater affinity for GABA
Additionally, in MDD, aberrant DNA methylation at stress-related loci, including the glucocorticoid receptor gene NR3C1 and FKBP5 and neurotrophic genes (such as BDNF ) are well documented 9
