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Growth factor signaling in injury models

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On the other hand, drug transport may occur via extracellular mechanisms, such as bulk flow along perineural channels and paracellular diffusion through epithelial tight junctions, as well as intracellular mechanisms, including endocytosis into epithelial or neuronal cells followed by transcytosis and axonal transport (Arora et al., 2002, Dhuria et al., 2010, Illum, 2000, Pires et al., 2009)