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Additionally, the epididymal white adipose tissue, one of the major triglyceride storage tissues, was found not to be impacted by the loss of Gclc and reduced triglycerides in the Gclc L-KO mice (Fig

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However, direct hormone replacement often bypasses the bodys natural endocrine feedback loops, leading to potential metabolic complications, receptor downregulation, and significant costs that limit long-term clinical utility

Crohns disease Crohns disease is a global disease affecting over 2 million individuals in North America, 3.2 million in Europe, and millions more worldwide
