l-carnitine fatty acid transport mitochondria Activation and Transportation of Acids to the via the Carnitine Shuttle with Animation Role of L-carnitine in the

Pediatrics 1981;67(1):95-100

Bohles and coworkers [81] investigated the effects of carnitine supplementation in 69 children and young adults treated with VPA monotherapy

Adjunctive Therapy Study Median Incidence of CPS per 8 Weeks * Reduction from baseline statistically significantly greater for valproate than placebo at p 0.05 level

Surprisingly, very similar prediction results with AUROC = 0.80 was established in this external validation cohort, suggesting that these microbiome features can be used to distinguish and predict human TMAO producer phenotypes from carnitine metabolism and have adequate potential to be applied in different populations