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For the LEfSe analysis, an alpha of 0.05 was set for the KruskalWallis tests among classes, and per-sample normalization was performed to bring the sum of the values to 1 M

This targeted distribution contributes to the favorable side effect profile relative to systemic weight loss interventions like stimulants

It is manufactured to achieve a purity level exceeding 99%, verified through high-performance liquid chromatography (HPLC) and liquid chromatography-mass spectrometry (LC-MS) testing methods to ensure quality and consistency

In a 26-week rat oral toxicity study, AOD-9604 produced dose-dependent changes in serum osteocalcin (a bone-turnover marker) at week 13, with the direction reversing by week 26