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Laryngoscope (2011) 121(9):18649

A recent study reported that IECs in Crohn's disease indeed exhibit impaired GPX4 activity and an increase of 4-hydroxy-2-nonenal (4-HNE) immunoreactivity, indicating a vulnerability of IECs to ferroptosis in Crohn's disease [352], although the therapeutic potential of targeting ferroptosis for Crohn's disease remains elusive

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