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Description
JAK2 engagement

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The GPCR arranges itself into a tertiary structure resembling a barrel, with the seven transmembrane helices forming a cavity within the plasma membrane that serves a ligand-binding domain that is often covered by EL-2

GSH Depletion as an Experimental Approach to Sensitize Tumor Cells to Therapy Cancer cell lines containing low GSH levels have been demonstrated to be much more sensitive than control cells to the effect of irradiation [18]
