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It has also been studied for heart health and bone density

Given that these studies utilized methods to assess dietary intake as a means of measuring vitamin B12 status, this may have resulted in an unreliable memory of individual dietary habits or errors in measurement, which could have influenced the final measurements of the aforementioned connections

This happens within minutes of administration in animal models

In the case of water-soluble vitamins like B12, vitamin C, folic acid, and other B vitamins, some medically reviewed literature points to early morning as the optimal time to take them as they can be taken on an empty stomach, but more peer-reviewed research is needed to confirm this claim