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Maintaining adequate vitamin D levels will reduce oxidative stress and improve mitochondrial function since a deficiency in vitamin D can affect the mitochondrial electron transport chain to reduce its efficiency, commonly resulting in increased oxidative stress and formation of ROS [124]

Improve Brain Function Along with helping the formation of red blood cells, B-12 also maintains the nerve that optimizes signaling from your brain

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Antidepressants like SSRI/SNRI/doxepin or hydroxyzine (if severe pruritus) are effective and a short course of BZD may be helpful during bouts of severe anxiety