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Many potentially toxic electrophilic xenobiotics and some endogenous compounds are detoxified by conversion to the corresponding glutathione S-conjugate, which is metabolized to the N-acetylcysteine S-conjugate (mercapturate) and excreted
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Nickel chromatography is a popular choice for affinity purifications due to its rapid and specific binding, speed, flexible and gentle elution conditions, and affordability
