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Moreover, GSH conjugation had a reliable role in bioactivating of most of moderately-active compounds to be highly active ones [12, 15, 73, 78]

2 The core function of macrophages As pivotal components of the innate immune system, macrophages play an indispensable role in maintaining tissue homeostasis, eliminating pathogens and aberrant cells, and initiating and modulating adaptive immunity through their potent phagocytic capacity, precise efferocytosis, and professional antigen presentation capabilities

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