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Identification of DIO2 as a new susceptibility locus for symptomatic osteoarthritis

USA 104 , 95979602 (2007)

10.1017/S004393391500029X 57

The release of iron ions by lysosomes through the degradation of ferritin mediated by autophagy increases intracellular free iron ion content, thereby promoting ferroptosis [6, 77, 78]

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