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Silibinin intervenes in cancer through epigenetic modifications Silibinin exerts its anti-cancer effects via epigenetic mechanisms, notably through the modulation of miRNA expression and the consequent dysregulation of their target genes, alongside alterations in DNA methylation patterns [947, 952, 953]
ROP1-mediated localization of NADPH oxidases orchestrates ROS production and guides pollen tube elongation (Smirnova et al., 2014)
Our meta-analysis is consistent with the results of these previous studies and, as far as we know, this is the first meta-analysis assessing the impact of AOX on TAC and MDA
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