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Metformin and vitamin B 12 deficiency Metformin-induced vitamin B 12 deficiency was reported as early as 1971 when Tomkin et al
Always inject close to the affected area for maximum benefit
3.2.3 FUNDC1 mediated mitophagy The FUN14 domain-containing protein 1 (FUNDC1) is widely present on the mitochondrial outer membrane and acts as a regulator of mitochondrial autophagy in response to hypoxia, inducing Parkin-independent mitophagy (Liu et al., 2012)
