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Chemically, 1 O is a highly reactive species with a short lifespan of 4100 s
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In contrast, loss of fmo-2 , a gene highly induced by tBOOH and completely dependent on nhr-49 for induction, paradoxically increased worm survival in this context (Goh et al., 2018), perhaps because FMO-2s predicted oxidase activity leads to ROS production, exacerbating the stress
The authors reported an increased risk of ASD with antibiotic exposure (aHR 1.10, 95% CI 1.01, 1.19)
