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LC-HRMS equipment costs hundreds of thousands of dollars, requires specialized operators, and takes significantly longer to process samples than a standard immunoassay strip

Except for patients with Hunner lesions (Statement 19), initial treatment should be nonsurgical

The peptide influences vasomotor tone through the Src-caveolin-1-eNOS pathway, affecting both vasoconstriction and vasodilation depending on baseline vascular state
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