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The likely mechanism underlying this ACE inhibitor-induced protection is a reduction in the synthesis of AngII acting at the AT 1 receptor subtype [reviewed in Ref
In this regard, murine brains undergoing HSV-1 encephalitis displayed chronic inflammation accompanied by moderately-elevated levels of F2-IP, while F4-NP levels remained normal (Milatovic et al., 2002)
This slowdown can contribute to a duller complexion and a less vibrant, youthful appearance
