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The different hGSTP1-1 mutants show slightly altered regioselectivities in the formation of the individual GSH conjugates of clozapine which suggests that the binding orientation of the reactive nitrenium ion of clozapine is affected by the mutations [34]

Intrinsic disorders can be divided into abnormalities of the RBC membrane, metabolic enzymes, or hemoglobin

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Unbalancing cAMP and Ras/MAPK pathways as a therapeutic strategy for cutaneous neurofibromas