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Interestingly, a recent study using a heavy isotope steady-state infusion of BCAA, showed a shift in BCAA oxidation from adipose tissue and liver toward skeletal muscle in obese, insulin resistant mice [84], consistent with the finding that BCKD enzyme activity in liver and adipose tissue is downregulated in animals with obese/insulin-resistant or diabetic states [75, 103, 111, 112, 134,135,136,137,138]

Alternative Medicine Review, 2006

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Eating more oily fish with a plant-based diet low in saturated fats may benefit patients who have CKD or those at risk of developing it (8)
