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The peptide increases collagen fiber organization and cross-linking, producing repairs that more closely resemble healthy tendon structure rather than disorganized scar tissue

But several factors work against this natural recovery process, including age (collagen production drops roughly 1% per year after age 20), the amount of weight lost (more than 50 pounds creates significantly more laxity), how long the excess weight was carried, sun damage history, smoking, genetics, and the speed at which the weight came off

The ROS-mediated damage is further enhanced in older individuals since during aging, GSH levels appear to diminish in numerous tissues, thereby placing cells at increased risk of stress-related death (Maher, 2005)