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Alternatively, new molecules may be designed based on rosiglitazone structure

BMC Genomics 7:142 van Swelm RPL, Laarakkers CMM, van der Kuur EC, Morava-Kozicz E, Wevers RA, Augustijn KD, Touw DJ, Sandel MH, Masereeuw R, Russel FGM (2012) Identification of novel translational urinary biomarkers for acetaminophen-induced acute liver injury using proteomic profiling in mice

Reviews have underlined that there is still no evidence connecting antibody alterations to long-term clinical outcomes such as better thyroid function or a slower progression to overt hypothyroidism, meaning that the certainty of the evidence is still low to moderate