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[PubMed: 15017362] 530

Construction of the high-throughput screening method In order to further improve the enzyme activity of Ch PPK and its tolerance to the substrate phosphate polyP, we screened Ch PPK mutants that could efficiently use polyP in the ATP regeneration system to enhance the supply of ATP in the biocatalytic process

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For example, it reduces 7-ketocholesterol-induced endothelial damage, suppresses pro-inflammatory cytokines, and preserves tight junction protein integrity in a brain microvascular endothelial hCMEC/D3 cell line [20]