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76 In a randomized placebo-controlled trial of 60 teenaged females on a 10-week modest weight-loss diet, curcumin consumption (500 mg/day) produced a substantial reduction in hs-CRP and IL-6

Based on these properties, AAV9 was investigated in mice models of spinal muscular atrophy (SMA), a monogenic disease characterized by the degeneration of the spinal motor neurons, with positive results in motor neuron survival, reversal of the phenotype and increased survival (Dominguez et al

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Goldspinks laboratory at the Medical College of Wisconsin has specifically characterised IGF-1 isoform activity in cardiac tissue, demonstrating MGFs role in preventing cardiomyocyte death, preserving contractility, and preventing pathological hypertrophy following myocardial infarction in animal studies