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Glucagon-like peptide-1 receptor agonist (GLP-1RA) and sodium-glucose cotransporter 2 inhibitor (SGLT2i) are currently recommended as first-line hypoglycaemic agents for patients with diabetes with established cardiovascular disease or multiple cardiovascular and renal risks [10]

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Microbially generated fatty acid ketones include 12( Z )-10-oxo-OME 9 and 11( E )-10-oxo-OME 10 (Scheme 57) derived from LA as well as the corresponding compounds formed from ALA